Jeong-Won Jeong, PhD

Professor of Pediatrics, Neurology, and Translational Neuroscience Program

Wayne State University School of Medicine, Detroit, MI

Email: jjeong@med.wayne.edu

Biography

Dr. Jeong is an MRI physicist and neuroimaging researcher. He received a B.S in Biomedical Engineering from Yonsei University, Korea, a M.S. in the Ming Hsieh Department of Electrical and Computer Engineering from the University of Southern California (USC),  Los Angeles, CA, and a Ph.D. in the USC Alfred E. Mann Department of Biomedical Engineering. He completed a postdoctoral fellowship at the USC Keck School of Medicine Radiology and Alfred E. Mann Institute for Biomedical Engineering.

His training and experience in MRI techniques place him uniquely to design and implement advanced research projects to benefit young patients with neurological disorders. He has always tried to use his abilities to help children afflicted with neurological diseases so that they can enjoy life and live it to the fullest. His research and clinical interest primarily include: functional and structural imaging biomarkers for the diagnosis of Epilepsy, Developmental Delay, Autisms, Sturge Weber Syndrome, and Borderline Personality Disorder. He has more than 80 peer-reviewed full papers, is the principal investigator of an R01 grant project funded by the National Institutes of Health to study an advanced diffusion MRI tractography methodology minimizing postoperative deficits in pediatric epilepsy surgery.  He is a Co-Investigator on four additional R01s to develop advanced multimodal imaging methodologies including MRI, PET and electrocorticography in order to accurately detect early onset of pediatric neurological disorders. 

Research and Clinical Interests

Acknowledgement

Blender is a public project hosted on blender.org, licensed as GNU GPL, owned by its contributors. For that reason Blender is Free and Open Source software, forever. We appreciate Blender community for providing tools that are crucial to advance our visualization of human brain MRI at very high spatio-temporal resolution.

Grant Supports

     Role: Principal Investigator

     The major goal of this study is to utilize deep learning-based diffusion MRI techniques to optimize the surgical margin,  predict the      

         postoperative neurocognitive outcome, and determine the specific mechanism of postoperative brain reorganization in children  

         undergoing epilepsy surgery.

    Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS 2R01NS089659

    Role: Co-Investigator

    The major goal of this project is to localize the language areas and to predict language outcomes after epilepsy surgery,  using invasive 

        monitoring.

    Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS 2R01 NS064033

         Role: Co-Investigator

    The major goal of this project is to utilize advanced neuroimaging techniques as biomarkers of disease progression,       

         understand pathophysiology, and develop new approaches to improve neuro-cognitive outcome in children with      

         Sturge-Weber syndrome.

    Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS 2R01NS041922

Role: Co-Investigator

The goal of this project is to elucidate the role of tetrahydrobiopterin in perinatal brain injury in human mutations causing childhood movement disorders utilizing a strategy to decrease tetrahydrobiopterin levels with a knockout transgenic approach in the rabbit of sepiapterin reductase. 

Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS 2R01NS117146 

Role: Co-Investigator

The major goal of this project is to investigate the systemic integration of MRI as a surrogate marker and high speed sorting into the unique animal model to probe the biochemical basis of specific neuronal injury at a critical time point. 

Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS R01NS114972

Role: Mentor 

The goal of this grant to investigate the effect of sevoflurane anesthesia on the localization of epiletic brain regions during intraoperative procedure.

Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS  F30NS129239

Role: Faculty Sponsor/Mentor 

The goal of this grant to image neural propagation of infantile spasm and use it for the prediction of postsurgical outcomes.

Sponsor Name: National Institute of Neurological Disorders and Stroke - NINDS  F30NS115279

Publications

Selected Publications (www.ncbi.nlm.nih.gov/myncbi/jeong-won.jeong.1/bibliography/public/)