Since January 1994, the Translational Imaging Laboratory (TIL) at Wayne State University Medical School Pediatrics has been at the forefront of providing cutting-edge neuroimaging methods in PET, MRI, and intracranial EEG (iEEG) for both clinical and research purposes. Our services cater to patients of all ages, hailing from Michigan and beyond. In collaboration with Children's Hospital of Michigan, Wayne State University, and other esteemed members of the Detroit Medical Center, we are committed to sharing our advanced neuroimaging techniques and abundant data resources with the community.

Our primary objectives include the detection of seizure epileptic foci, the AI-based benefit-risk evaluation of epilepsy surgery, the longitudinal neuroimaging of Sturge-Weber Syndrome, the invasive mapping of human language network, the assessment of serotonin synthesis capacity in autism and tuberous sclerosis, the evaluation of heart disorders and cardiac viability, as well as the identification and monitoring of malignant diseases or tumors and their corresponding therapies. Through these critical endeavors, we strive to make significant contributions to medical knowledge and improve the lives of children and adults in our region and beyond.

• NIH-funded Project on Sturge-Weber Syndrome (PI: Csaba Juhasz)

• NIH-funded Project on Language localization (PI: Eishi Asano)

• NIH-funded Project on Pediatric Epilepsy Surgery (PI: Justin Jeong-Won Jeong)

• NIH-funded Project on Seizure Network Modeling (PI: Nolan O'Hara)

• NIH-funded Project on Seizure Localization (PI: Ethan Firestone)

• NIH funded project on tryptophan metablosm in human brain tumors (PI: Csaba Juhasz)

• NIH funded project on sympathetic innervation of cold-activated brown and white fat in lean young adult (PI: Otto Muzik)

• NIH funded project on quantitative assessment of oxidative metabolism in brain fat (PI: Otto Muzik)

• NIH funded project on software tools for pediatric neuroimaging (PI: Otto Muzik)

• NIH funded project on ontogeny of GABA A receptor complex measured with PET (PI: Otto Muzik)

• NIH funded project on neurodevelopmental outcomes assocaited with care setting in children orphaned by AIDS (PI: Michael Behen)

• NIH funded project on structureal and functional correlates of early postnatal depriveation (PI: Michael Behen)

• NIH funded project on diffuson tensor imaging biomarker in developmental delay (PI: Senthil Sundaram)

• NIH funded project on children with autism spectrum disorders in developing coutnries (PI: Diane Chugani)

• NIH funded project on early pharmacotherapy guided by biomarkers in autism (PI: Diane Chugani)

• NIH funded project on imaging tryptophan metabolism in children with epilepsy (PI: Diane Chugani)

• NIH funded project on imaging tryptophan metabolism in tuberous sclerosis (PI: Diane Chugani)

• NIH funded project on brain serotonin synthesis in autism (PI: Diane Chugani)

• NIH funded project on identifying epileptogenic tubers in TSC (PI: Harry Chugani)

• NIH funded project on sturge weber syndrome consensus conference (PI: Harry Chugani)

• NIH funded project on localization of epileptic foci with pet in children (PI: Harry Chugani)

• Independent Component Analysis tractography combined with a ball-stic model for clinical DTI data

• Deep convolutional neural network for objective detection of eloquent axonal pathways

• Deep vein segmentation and visualization in susceptibility weighted imaging 

• Dynamic tractography using Blender

• Deep learning-based tract classification for clinical diffusion tractography connectome