Min-Hee Lee, PhD
Assistant Professor
Department of Pediatrics, Wayne State University School of Medicine
E-mail: min-hee.lee@wayne.edu
Biography
Min-Hee Lee, Ph.D. is an Assistant Professor of Pediatrics, Wayne State University. Dr. Lee received a doctorate in Biomedical Engineering from Yonsei University, Republic of Korea. Dr. Lee's main research area is translational neuroimaging to bridge the gap between basic neuroscience research and clinical practice. He focuses on using advanced imaging methods such as Magnetic Resonance Imaging (MRI) and Diffusion Weighted Imaging (DWI) to investigate the brain structure, with the ultimate goal of translating the findings into practical applications for predicting, diagnosing, and understanding neurological and psychiatric disorders. He aims to develop deep learning-based DWI technique to optimize the surgical margin, predict the postoperative neurocognitive outcome, and determine postoperative brain reorganization in children with epilepsy.
Selected Publications
https://www.ncbi.nlm.nih.gov/myncbi/1VI1inx73FrYqz/bibliography/public/
MH Lee, S Sin, S Lee, ME Wagshul, ME Zimmerman, R Arens. Cortical thickness and hippocampal volume in adolescent children with obstructive sleep apnea. Sleep, 46, zsac201, 2023.
MH Lee, CS Yun, K Kim, Y Lee. Image restoration algorithm incorporating methods to remove noise and blurring from positron emission tomography imaging for Alzheimer's disease diagnosis. Phys. Medica, 103, 181-189, 2022.
MH Lee, SK Lee, S Kim, REY Kim, HR Nam, AT Siddiquee, RJ Thomas, I Hwang, JE Yoon, CH Yun, C Shin. Association of obstructive sleep apnea with white matter integrity and cognitive performance over a 4-year period in middle to late adulthood. JAMA Netw. Open, 5, e2222999, 2022.
MH Lee, S Sin, S Lee, H Park, ME Wagshul, ME Zimmerman, R Arens. Altered cortical structure network in children with obstructive sleep apnea. Sleep, 45, zsac030, 2022.
MH Lee, YH Hwang, CS Yun, BS Han, DY Kim. Altered small-world property of a dynamic metabolic network in murine left hippocampus after exposure to acute stress. Sci. Rep., 12, 3885, 2022.
MH Lee, CS Yun, K Kim, Y Lee. Effect of denoising and deblurring 18F-fluorodeoxyglucose positron emission tomography images on a deep learning model’s classification performance for Alzheimer’s disease, Metabolites, 12, 231, 2022.
MH Lee, SK Lee, RJ Thomas, JE Yoon, CH Yun, C Shin. Deep learning-based assessment of brain connectivity related to obstructive sleep apnea and daytime sleepiness. Nat. Sci. Sleep, 13, 1561-1572, 2021.
K Kim, MH Lee, Y Lee. Investigation of a blind-deconvolution framework after noise reduction using a gamma camera in nuclear medicine imaging. Nucl. Eng. Technol., 52, 2594-2600, 2020.
MH Lee, N O'Hara, M Sonoda, N Kuroda, C Juhász, E Asano, M Dong, JW Jeong. Novel deep learning network analysis of electrical stimulation mapping-driven diffusion MRI tractography to improve preoperative evaluation of pediatric epilepsy. IEEE Trans. Biomed. Eng., 67, 3151-3162, 2020.
MH Lee, N O'Hara, ME Behen, JW Jeong. Altered efficiency of white matter connections for language function in children with language disorder. Brain Lang., 203, 104743, 2020.
MH Lee, N O'Hara, H Motoi, AF Luat, C Juhász, S Sood, E Asano, JW Jeong. Novel diffusion tractography methodology using Kalman filter prediction to improve preoperative benefit-risk analysis in pediatric epilepsy surgery, J. Neurosurg.-Pediatr., 24, 293-305, 2019.
MH Lee, CH Yun, A Min, YH Hwang, SK Lee, DY Kim, RJ Thomas, BS Han, C Shin. Altered structural brain network resulting from white matter injury in obstructive sleep apnea, Sleep, 42, zsz120, 2019.
MH Lee, N O'Hara, Y Nakai, AF Luat, C Juhász, S Sood, E Asano, JW Jeong. Prediction of postoperative deficits using an improved diffusion-weighted imaging maximum a posteriori probability analysis in pediatric epilepsy surgery, J. Neurosurg.-Pediatr., 23, 648-659, 2019 (Front Cover).
MH Lee, DY Kim, MK Chung, AL Alexander, RJ Davidson. Topological properties of the structural brain network constructed using the ε-neighbor method, IEEE Trans. Biomed. Eng., 65, 2323-2333, 2018 (Front Cover).
MH Lee, A Min, YH Hwang, DY Kim, BS Han, HS Seo. Structural brain network abnormalities in subjects with internet addiction, J. Mech. Med. Biol., 17, 1740031, 2017.
MH Lee, Y Lee, YH Hwang, A Min, BS Han, DY Kim. Impact of sleep restriction on the structural brain network, NeuroReport, 27, 1299-1304, 2016 (Cover paper).
MH Lee, Y Shin, SH Lee, YJ Cha, DY Kim, BS Han, SH You. Diffusion tensor imaging to determine the potential motor network connectivity between the involved and non-involved hemispheres in stroke, Bio-Med. Mater. Eng., 26, S1447-S1453, 2015 (Highlighted paper).
Examples of DCNN-determined tract classes spatially well-matched with ESM-determined eloquent areas.
The language related subnetwork.
Surgical resections that preserved the DWI-proposed preservation zone.
Eloquent pathways obtained from original DWI-MAPand improved DWI-MAP.